Mixcraft HD (32x32):

Pros >

- 32x32 pixels per block
- High definition text
- Custom water animations
- Better looking grass and trees

Cons >

- Less simple installation

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Mixcraft Basic (16x16):

Pros >

- Fast and Easy to install

Cons >

- 16x16 pixels per block
- Low definition text
- Default water animation
- Worse looking grass and trees